NAPLEX Practice Questions

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🎯 Free NAPLEX Practice Questions
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Disclaimer: These practice questions are intended as a study aid and do not cover all topics that may appear on the NAPLEX. Questions are periodically reviewed and updated, but it remains the user’s responsibility to stay informed on the most current clinical guidelines and NAPLEX content areas. Always refer to the latest official sources and recommendations when preparing for the exam.

NAPLEX Practice Questions

1 / 10

1. A patient needs long-term prophylaxis to reduce gout flare frequency. Which of the following are appropriate options?

A. Allopurinol

B. Febuxostat

C. Prednisone

D. A and B only

E. All of the above

2 / 10

2. Select the mechanism of action of donepezil:

A. Decarboxylase inhibitor

B. Norepinephrine reuptake inhibitor

C. Acetylcholinesterase inhibitor

D. Anticholinergic

E. NMDA-receptor antagonist

3 / 10

3. How can the incorrect use of antithrombotics be minimized in hospitalized patients?

A. Use dosing protocols

B. Monitor INRs as scheduled

C. Educate patients and involve dietitians

D. A and B only

E. All of the above

4 / 10

4. Which of the following strategies helps minimize the risk of calcium-phosphate precipitation in a TPN formulation?

A. Use calcium chloride instead of calcium gluconate

B. Add phosphate first, mix thoroughly, then add calcium last

C. Increase the temperature of the TPN bag to enhance solubility

D. Ensure calcium + phosphate total exceeds 50 mEq/L

E. Use high-pH amino acid solutions to stabilize solubility

5 / 10

5. An 72-year-old female has T-scores of -4.2 in her spine and -3.4 in her right hip without history of fractures. What condition is indicated?

A. More testing is needed to make a diagnosis.

B. These results indicate osteopenia.

C. These results indicate osteoporosis.

D. The patient does not have osteopenia or osteoporosis.

6 / 10

6. A pharmacist dissolves 3 ketoconazole tablets, each containing 200 mg, into a base to prepare 30 mL of a topical solution. What is the % strength (w/v)?

A. 1.8%

B. 2%

C. 2.5%

D. 1.5%

E. 0.2%

7 / 10

7. What controlled category is Sonata?

A. C I

B. C II

C. C III

D. C IV

E. C V

8 / 10

8. A patient hospitalized with acute myocardial infarction. What statin should they be started on to reduce risk of recurrent ischemia?

A. Simvastatin 40 mg

B. Lovastatin 80 mg

C. Rosuvastatin 10 mg

D. Atorvastatin 80 mg

E. Pravastatin 40 mg

9 / 10

9. A patient is admitted with ataxia, dizziness, and slurred speech. Phenytoin toxicity is suspected. Laboratory values show: phenytoin level 12.6 mcg/mL (therapeutic 10-20 mcg/mL) and albumin 1.6 g/dL (normal range 3.6-5.1 g/dL). What is the most appropriate interpretation of these findings?

A. Albumin level is actually higher

B. Albumin level is actually lower

C. Phenytoin level is actually higher

D. Phenytoin level is actually lower

E. None of the above

10 / 10

10. The patient is trying to dispose of unused medications but does not want to flush them. In the absence of a take-back program, what should the pharmacist advise?

A. Remove the medications from their original containers and mix them with an unappealing substance, such as used coffee grounds or cat litter.

B. Place the mixture in a sealable bag or a disposable container with a secure lid, like an empty margarine tub.

C. Protect your privacy by removing or obscuring any personal information on the prescription labels using a black marker, duct tape, or by scratching it off.

D. Dispose of the sealed container and the defaced prescription bottles in your regular household trash.

E. All of the above

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