NAPLEX Practice Questions

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🎓 FREE NAPLEX Practice Questions – Test Your Knowledge Now!

🎯 Free NAPLEX Practice Questions
Test your knowledge with a mix of high-yield, exam-style questions.

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Disclaimer: These practice questions are intended as a study aid and do not cover all topics that may appear on the NAPLEX. Questions are periodically reviewed and updated, but it remains the user’s responsibility to stay informed on the most current clinical guidelines and NAPLEX content areas. Always refer to the latest official sources and recommendations when preparing for the exam.

NAPLEX Practice Questions

1 / 10

1. Amy takes dornase alfa for cystic fibrosis. What is the correct statement regarding dornase alfa?

A. Reduces mucus viscosity and improves airflow

B. Taken as a 25 mg ampule nebulized daily

C. Store at room temp and protect from light

D. Brand name is Xolair

E. All of the above

2 / 10

2. Aurora has monthly migraines triggered by her menstrual cycle which is accompanied by heavy bleeding. Which option would be appropriate to prevent migraines in her case?

A. Sumatriptan

B. Propranolol to reduce migraines

C. Oral contraceptives

D. A migraine patch

E. Fioricet for pain management

3 / 10

3. A heart failure patient was started on Vasotec 2.5mg twice daily and Toprol XL 25 mg daily. During the one month follow-up the patient's blood pressure is 120/80 mmgHg and heart rate at 75 BPM. The patient developed a dry cough and drinking water doesn't help. What medication changes are appropriate?

A. Use OTC cough suppressant

B. Stop Toprol XL and start carvedilol

C. Switch from Vasotec to Diovan

D. Reduce Toprol XL dose

E. Reduce Vasotec dose

4 / 10

4. A prescription calls for 54 grams of polyethylene glycol 400. If the specific gravity is 1.13, how many milliliters are required?

A. 58.3 mL

B. 20 mL

C. 47.8 mL

D. 50 mL

E. 46.29 mL

5 / 10

5. If 1 gallon of a 20% (w/v) solution is evaporated to a solution with a 40% (w/v) strength, what will be the new volume (in mL)?

A. 710 mL

B. 1666 mL

C. 1776 mL

D. 1893 mL

E. 2840 mL

6 / 10

6. An 75-year-old male with end stage renal disease is currently on venlafaxine, warfarin, lisinopril, and potassium. He had a recent serious bleed. What is the most likely cause?

A. Bleeding risk from warfarin and lisinopril

B. Increased bleed risk from warfarin and venlafaxine

C. Fall risk due to end stage renal disease and venlafaxine

D. A and B

E. None of the above

7 / 10

7. A patient decideds to take OTC pseudoephedrine for bad congestion. Which is a known side effect of pseudoephedrine?

A. Tachycardia

B. Drowsiness

C. Increased appetite

D. Decreased blood pressure

E. All of the above

8 / 10

8. A 17-year-old female is picking up her oral contraceptive pills. The pharmacist wants to ensure she is maintaining an adequate intake of which B vitamin, which may be depleted with oral contraceptive use?

A. Folic acid

B. Pyridoxine

C. Riboflavin

D. Thiamine

E. Cobalamin

9 / 10

9. James is a 65-year-old male newly prescribed tamsulosin for benign prostatic hyperplasia. Which of the following statements is correct?

A. The correct dose is 4 mg daily

B. Tamsulosin is a dopamine agonist

C. Tamsulosin blocks alpha-1 receptors in prostate tissue

D. It causes frequent erectile dysfunction

E. It is only used for prostate cancer

10 / 10

10. A patient is admitted with ataxia, dizziness, and slurred speech. Phenytoin toxicity is suspected. Laboratory values show: phenytoin level 12.6 mcg/mL (therapeutic 10-20 mcg/mL) and albumin 1.6 g/dL (normal range 3.6-5.1 g/dL). What is the most appropriate interpretation of these findings?

A. Albumin level is actually higher

B. Albumin level is actually lower

C. Phenytoin level is actually higher

D. Phenytoin level is actually lower

E. None of the above

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