NAPLEX Practice Questions

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🎓 FREE NAPLEX Practice Questions – Test Your Knowledge Now!

🎯 Free NAPLEX Practice Questions
Test your knowledge with a mix of high-yield, exam-style questions.

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Disclaimer: These practice questions are intended as a study aid and do not cover all topics that may appear on the NAPLEX. Questions are periodically reviewed and updated, but it remains the user’s responsibility to stay informed on the most current clinical guidelines and NAPLEX content areas. Always refer to the latest official sources and recommendations when preparing for the exam.

NAPLEX Practice Questions

1 / 10

1. A patient is receiving 400 mL of 10% Intralipid weekly. How many kcal from lipids are provided daily?

A. 62.9 kcal

B. 550 kcal

C. 78.6 kcal

D. 74.8 kcal

E. 550.8 kcal

2 / 10

2. A 62-year-old man taking tamsulosin is prescribed sildenafil for erectile dysfunction. What should the pharmacist advise?

A. The combination is contraindicated.

B. He should be warned about dizziness and fainting.

C. Start sildenafil at 25 mg daily.

D. Switch to terazosin instead.

E. None of the above

3 / 10

3. A patient on long-term antiretroviral therapy starts to shows drug resistance. His CD4+ count is 330 cells/?L. Which medication is recommended to prevent an opportunistic infection?

A. Start Trimethoprim-sulfamethoxazole single strength daily

B. Start Trimethoprim-sulfamethoxazole double strength daily

C. Start azithromycin weekly.

D. B and C only

E. Do not start any prophylactic medications for now.

4 / 10

4. Maria is a 30-year-old woman with lupus nephritis. Her renal function has progressively declined, and her estimated creatinine clearance is 23 mL/min. Her serum potassium is 4.8 mEq/L. Current medications include enalapril, hydroxychloroquine, a vitamin D supplement, and atorvastatin. Maria is seeking a reliable form of contraception. Which of the following contraceptive methods would be inappropriate for Maria given her current clinical status?

A. Yasmin

B. Yaz

C. IUD

D. A and B

E. All of the above

5 / 10

5. What is the correct way to use the Daytrana patch?

A. Apply to the hip 2 hours before the medication is needed

B. Replace weekly

C. Switch application site on opposite hip every week

D. Press patch for 5 seconds when applying

E. Remove during bathing or showering

6 / 10

6. A patient with multiple sclerosis is being started on Tysabri. What serious adverse effect limits its routine use?

A. Progressive multifocal leukoencephalopathy

B. Renal tubular necrosis

C. Liver failure

D. Acute cardiac ischemia

E. Severe allergic reaction

7 / 10

7. An 75-year-old male with end stage renal disease is currently on venlafaxine, warfarin, lisinopril, and potassium. He had a recent serious bleed. What is the most likely cause?

A. Bleeding risk from warfarin and lisinopril

B. Increased bleed risk from warfarin and venlafaxine

C. Fall risk due to end stage renal disease and venlafaxine

D. A and B

E. None of the above

8 / 10

8. A 40-year-old male with atrial fibrillation has been on long-term warfarin 2 mg daily, well controlled. He recently started amiodarone and sertraline with no changes to warfarin dosing. He was admitted to the emergency room with bleeding gums and black tarry stool. The INR at the emergency room was 8 with hemoglobin 8.3 g/dL. What is the correct course of action:

A. Hold warfarin and give 1–2.5 mg vitamin K orally.

B. Omit next 1–2 doses and monitor INR.

C. Hold warfarin and give 2 mg vitamin K SC.

D. Hold warfarin and give vitamin K 10 mg slow IV infusion.

E. Hold warfarin and give vitamin K 10 mg IM.

9 / 10

9. A patient begins Plaquenil for lupus. What are important counseling points?
I. The drug is dosed three times per day.
II. Visual and auditory changes should be monitored.
III. Lab tests should monitor for increased platelets.
IV. Take with meals to reduce GI upset.

A. 1 and 2

B. 2 and 3

C. 3 and 4

D. 2 and 4

E. 1, 2, 3 and 4

10 / 10

10. Emily has a long-standing history of psychosis and anxiety. She presents to the clinic with an involuntary, rhythmic movement of the neck that is painful. Which of her current medications is the most likely cause of this drug-induced movement disorder?

A. Lorazepam

B. Chlorpromazine

C. Carvedilol

D. Albuterol

E. Pregabalin

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