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NAPLEX Practice Exam A

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NAPLEX Practice Questions

1 / 10

1. What is the correct way to use the Daytrana patch?

A. Apply to the hip 2 hours before the medication is needed

B. Replace weekly

C. Switch application site on opposite hip every week

D. Press patch for 5 seconds when applying

E. Remove during bathing or showering

Daytrana is applied daily, to the hip, 2 hours before effect is desired, and held for 30 seconds. Alternate hips daily. It is water-resistant.

2 / 10

2. A patient on chronic omeprazole therapy is concerned about nutrient absorption. Which of the following agents may have reduced absorption with acid suppression?

A. Iron

B. Itraconazole

C. Acetaminophen

D. Tetracycline

E. A and B only

Many drugs require an acidic environment for optimal absorption, including iron, azole antifungals, and certain antibiotics. Chronic acid suppression can impair this.

3 / 10

3. What is the correct wear time for the scopolamine patch?

A. 1 day

B. 2 days

C. 3 days

D. 5 days

E. 7 days

Transderm Scop is a 72-hour patch; change every 3 days and apply in advance of expected motion sickness.

4 / 10

4. A patient with ulcerative colitis is prescribed sulfasalazine. What is an appropriate counseling point?

A. Common side effects include nausea and headache

B. This medication may cause red/orange discoloration of urine and skin.

C. This drug is well-tolerated in patients with sulfa allergies.

D. Take this medication on an empty stomach to enhance absorption.

E. A and B only

Sulfasalazine often causes nausea, headache, and reduced appetite. It's not the same as Asacol, and penicillin allergy is not a contraindication.

5 / 10

5. Which of the following strategies helps minimize the risk of calcium-phosphate precipitation in a TPN formulation?

A. Use calcium chloride instead of calcium gluconate

B. Add phosphate first, mix thoroughly, then add calcium last

C. Increase the temperature of the TPN bag to enhance solubility

D. Ensure calcium + phosphate total exceeds 50 mEq/L

E. Use high-pH amino acid solutions to stabilize solubility

Calcium and phosphate can precipitate in TPN if not carefully managed. Best practices include using calcium gluconate (less dissociation than calcium chloride), adding phosphate first and calcium last, using lower final concentrations, and ensuring proper refrigeration. Calcium and phosphate added should not exceed 45 mEq/L. Maintain proper pH (lower pH = less risk of precipitation). Refrigerate the bag once prepared.

6 / 10

6. Which auxiliary labels should accompany a benzodiazepine prescription?

A. Controlled substance warning

B. May cause drowsiness

C. Avoid alcohol

D. May impair driving

E. All of the above

All are appropriate due to CNS effects, abuse potential, and safety risks.

7 / 10

7. How many grams of dextrose are in 750 mL of D5W?

A. 10 grams

B. 25 grams

C. 37.5 grams

D. 50 grams

E. 125 grams

D5W = 5 g/100 mL --> 750 mL × 0.05 = 37.5 g

8 / 10

8. A patient on long-term antiretroviral therapy starts to shows drug resistance. His CD4+ count is 330 cells/?L. Which medication is recommended to prevent an opportunistic infection?

A. Start Trimethoprim-sulfamethoxazole single strength daily

B. Start Trimethoprim-sulfamethoxazole double strength daily

C. Start azithromycin weekly.

D. B and C only

E. Do not start any prophylactic medications for now.

Prophylaxis for OIs is not recommended until the CD4+ count drops below 200 for PCP and <50 for MAC.

9 / 10

9. A patient presents a prescription for Cozaar she needed filled. Her other medication is Yasmin contraceptive pills. The pharmacy is in a supermarket, and the pharmacist notices the patient has Morton Salt Balance in her shopping cart, which contains potassium chloride. The following are correct counseling statements:

A. Your new medication, and the salt substitute, can increase your potassium.

B. Yasmin can increase potassium.

C. Cozaar is not safe in pregnancy.

D. A and B.

E. All of the above

Both Cozaar (losartan) and Yasmin (ethinyl estradiol/drospirenone) can increase potassium levels. Additionally, potassium-containing salt substitutes can further increase potassium levels when taken with Cozaar. It's also important to note that Cozaar is contraindicated in pregnancy. Therefore, statements A and B are correct counseling points.

10 / 10

10. Which Alzheimer medication comes in oral disintegrating tablet form for dysphagia patients?

A. Tacrine

B. Donepezil

C. Rivastigmine

D. Galantamine

E. Memantine

Donepezil (Aricept) is the only one available as an ODT.

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