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NAPLEX Practice Exam A

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NAPLEX Practice Questions

1 / 10

1. Proper EpiPen instructions include all EXCEPT:

A. Hold injector tip down; pull off the cap

B. Remove pants prior to injection

C. Rub area after removing the injector. Look at the tip: If the needle is showing, the dose was received. If not, repeat dose.

D. After the shot, press the needle against a hard surface to bend the needle back. Put the injector back in its case, needle first. Do not put the cap back on the injector.

The pen can go through clothes; removing pants is not required and may delay use.

2 / 10

2. What controlled category is Sonata?

A. C I

B. C II

C. C III

D. C IV

E. C V

Sonata (zaleplon) is a C IV controlled substance like other non-BZDs.

3 / 10

3. A 78-year-old woman prescribed oxybutynin ER for overactive bladder is most likely to experience which side effect?

A. Hypoglycemia

B. Orthostatic hypotension

C. Dry mouth

D. Tachycardia

E. Rash

Oxybutynin is an anticholinergic that frequently causes dry mouth, along with constipation, dizziness, and blurry vision.

4 / 10

4. What is the brand name of triamcinolone when used in asthma?

A. Asmanex HFA

B. Aerospan HFA

C. Nasacort AQ

D. Azmacort

E. Nasonex

Triamcinolone for asthma is marketed as Azmacort; Nasacort AQ is for allergic rhinitis.

5 / 10

5. Maria is a 30-year-old woman with lupus nephritis. Her renal function has progressively declined, and her estimated creatinine clearance is 23 mL/min. Her serum potassium is 4.8 mEq/L. Current medications include enalapril, hydroxychloroquine, a vitamin D supplement, and atorvastatin. Maria is seeking a reliable form of contraception. Which of the following contraceptive methods would be inappropriate for Maria given her current clinical status?

A. Yasmin

B. Yaz

C. IUD

D. A and B

E. All of the above

Maria is taking lisinopril and has CKD. Combined oral contraceptives like Yaz and Yasmin contain drospirenone, which is potassium-sparing. Her renal impairment and ACE inhibitor use increase the risk of hyperkalemia.

6 / 10

6. A patient needs long-term prophylaxis to reduce gout flare frequency. Which of the following are appropriate options?

A. Allopurinol

B. Febuxostat

C. Prednisone

D. A and B only

E. All of the above

Allopurinol and febuxostat are used for prevention, not corticosteroids like prednisone, which are for acute flares.

7 / 10

7. A patient on long-term antiretroviral therapy starts to shows drug resistance. His CD4+ count is 330 cells/?L. Which medication is recommended to prevent an opportunistic infection?

A. Start Trimethoprim-sulfamethoxazole single strength daily

B. Start Trimethoprim-sulfamethoxazole double strength daily

C. Start azithromycin weekly.

D. B and C only

E. Do not start any prophylactic medications for now.

Prophylaxis for OIs is not recommended until the CD4+ count drops below 200 for PCP and <50 for MAC.

8 / 10

8. What are recommended non-drug interventions for pulmonary hypertension?

A. Sodium restriction to less than 2.4 grams per day

B. Avoiding exposure to high altitudes

C. Maintaining a constant fluid volume status

D. Routine immunization with influenza and pneumococcal vaccines

E. All of the above

Sodium restriction, fluid control, and avoiding altitude are all part of supportive PAH care.

9 / 10

9. An 72-year-old female has T-scores of -4.2 in her spine and -3.4 in her right hip without history of fractures. What condition is indicated?

A. More testing is needed to make a diagnosis.

B. These results indicate osteopenia.

C. These results indicate osteoporosis.

D. The patient does not have osteopenia or osteoporosis.

A T-score below -2.5 is diagnostic for osteoporosis.

10 / 10

10. A patient taking levothyroxine also uses OTC medications for heartburn. Which of the following is least likely to interfere with thyroid hormone absorption?

A. Magnesium hydroxide

B. Calcium carbonate

C. Famotidine

D. Pepcid Complete

E. C and D only

Calcium and magnesium-based antacids can impair levothyroxine absorption. Famotidine, an H2 blocker, does not affect absorption, but combination products may. Pepcid Complete contains famotidine and antacids.

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