NAPLEX Practice Questions

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🎓 FREE NAPLEX Practice Questions – Test Your Knowledge Now!

🎯 Free NAPLEX Practice Questions
Test your knowledge with a mix of high-yield, exam-style questions.

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Disclaimer: These practice questions are intended as a study aid and do not cover all topics that may appear on the NAPLEX. Questions are periodically reviewed and updated, but it remains the user’s responsibility to stay informed on the most current clinical guidelines and NAPLEX content areas. Always refer to the latest official sources and recommendations when preparing for the exam.

NAPLEX Practice Questions

1 / 10

1. Which auxiliary labels should accompany a benzodiazepine prescription?

A. Controlled substance warning

B. May cause drowsiness

C. Avoid alcohol

D. May impair driving

E. All of the above

2 / 10

2. A patient is admitted with ataxia, dizziness, and slurred speech. Phenytoin toxicity is suspected. Laboratory values show: phenytoin level 12.6 mcg/mL (therapeutic 10-20 mcg/mL) and albumin 1.6 g/dL (normal range 3.6-5.1 g/dL). What is the most appropriate interpretation of these findings?

A. Albumin level is actually higher

B. Albumin level is actually lower

C. Phenytoin level is actually higher

D. Phenytoin level is actually lower

E. None of the above

3 / 10

3. Which of the following strategies helps minimize the risk of calcium-phosphate precipitation in a TPN formulation?

A. Use calcium chloride instead of calcium gluconate

B. Add phosphate first, mix thoroughly, then add calcium last

C. Increase the temperature of the TPN bag to enhance solubility

D. Ensure calcium + phosphate total exceeds 50 mEq/L

E. Use high-pH amino acid solutions to stabilize solubility

4 / 10

4. How many grams of dextrose are in 750 mL of D5W?

A. 10 grams

B. 25 grams

C. 37.5 grams

D. 50 grams

E. 125 grams

5 / 10

5. A 10 g packet of potassium chloride provides 20 mEq of K and 4 mEq of Cl. How many grams would provide 12 mEq of potassium?

A. 7 grams

B. 4.5 grams

C. 3.9 grams

D. 6 grams

E. 1/2 packet

6 / 10

6. Which Alzheimer medication comes in oral disintegrating tablet form for dysphagia patients?

A. Tacrine

B. Donepezil

C. Rivastigmine

D. Galantamine

E. Memantine

7 / 10

7. A heart failure patient was started on Vasotec 2.5mg twice daily and Toprol XL 25 mg daily. During the one month follow-up the patient's blood pressure is 120/80 mmgHg and heart rate at 75 BPM. The patient developed a dry cough and drinking water doesn't help. What medication changes are appropriate?

A. Use OTC cough suppressant

B. Stop Toprol XL and start carvedilol

C. Switch from Vasotec to Diovan

D. Reduce Toprol XL dose

E. Reduce Vasotec dose

8 / 10

8. Maria is a 30-year-old woman with lupus nephritis. Her renal function has progressively declined, and her estimated creatinine clearance is 23 mL/min. Her serum potassium is 4.8 mEq/L. Current medications include enalapril, hydroxychloroquine, a vitamin D supplement, and atorvastatin. Maria is seeking a reliable form of contraception. Which of the following contraceptive methods would be inappropriate for Maria given her current clinical status?

A. Yasmin

B. Yaz

C. IUD

D. A and B

E. All of the above

9 / 10

9. A 67-year-old man presents to the emergency department 1 hour after the sudden onset of right-sided weakness and slurred speech which occured 1 hr ago. A non-contrast CT scan of the head shows no evidence of hemorrhage. His blood pressure is 190/92 mmHg, and blood glucose is 110 mg/dL. His past medical history includes hypertension, type 2 diabetes, and peptic ulcer disease. His current medications include lisinopril, metformin, enoxaparin, and aspirin. Further review of the electronic medical record reveals that he underwent a lumbar laminectomy 10 days ago.

Which of the following is the most appropriate next step regarding administration of alteplase (tPA)?

A. Administer alteplase within the next 2 hours.

B. Do not administer alteplase due to recent surgery.

C. Administer alteplase after administering a loading dose of aspirin.

D. Administer alteplase only if blood pressure is lowered to below 185/110 mmHg.

E. Administer alteplase after discontinuing enoxaparin for 24 hours

10 / 10

10. Amy takes dornase alfa for cystic fibrosis. What is the correct statement regarding dornase alfa?

A. Reduces mucus viscosity and improves airflow

B. Taken as a 25 mg ampule nebulized daily

C. Store at room temp and protect from light

D. Brand name is Xolair

E. All of the above

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